000 - Document - Document And Entity Information link:calculationLink link:definitionLink link:presentationLink 001 - Statement - Consolidated Balance Sheets link:calculationLink link:definitionLink link:presentationLink 002 - Statement - Consolidated Balance Sheets (Parentheticals) link:calculationLink link:definitionLink link:presentationLink 003 - Statement - Consolidated Statements of Operations link:calculationLink link:definitionLink link:presentationLink 004 - Statement - Consolidated Statements of Operations (Parentheticals) link:calculationLink link:definitionLink link:presentationLink 005 - Statement - Consolidated Statements of Comprehensive Income (Loss) link:calculationLink link:definitionLink link:presentationLink 006 - Statement - Consolidated Statements of Stockholders' Equity link:calculationLink link:definitionLink link:presentationLink 007 - Statement - Consolidated Statements of Cash Flows link:calculationLink link:definitionLink link:presentationLink 008 - Disclosure - Note 1 - Nature of Business and Financial Condition link:calculationLink link:definitionLink link:presentationLink 009 - Disclosure - Note 2 - Summary of Significant Accounting Policies link:calculationLink link:definitionLink link:presentationLink 010 - Disclosure - Note 3 - Miscellaneous Financial Information link:calculationLink link:definitionLink link:presentationLink 011 - Disclosure - Note 4 - Restricted Cash and Restricted Cash Equivalents link:calculationLink link:definitionLink link:presentationLink 012 - Disclosure - Note 5 - Marketable Securities link:calculationLink link:definitionLink link:presentationLink 013 - Disclosure - Note 6 - Axens License link:calculationLink link:definitionLink link:presentationLink 014 - Disclosure - Note 7 - Intangible Assets link:calculationLink link:definitionLink link:presentationLink 015 - Disclosure - Note 8 - Revenues From Contracts With Customers and Other Revenue link:calculationLink link:definitionLink link:presentationLink 016 - Disclosure - Note 9 - Leases, Right-of-use Assets and Related Liabilities link:calculationLink link:definitionLink link:presentationLink 017 - Disclosure - Note 10 - Inventories link:calculationLink link:definitionLink link:presentationLink 018 - Disclosure - Note 11 - Property, Plant and Equipment link:calculationLink link:definitionLink link:presentationLink 019 - Disclosure - Note 12 - Embedded Derivatives link:calculationLink link:definitionLink link:presentationLink 020 - Disclosure - Note 13 - Accounts Payable and Accrued Liabilities link:calculationLink link:definitionLink link:presentationLink 021 - Disclosure - Note 14 - Debt link:calculationLink link:definitionLink link:presentationLink 022 - Disclosure - Note 15 - Equity Incentive Plans link:calculationLink link:definitionLink link:presentationLink 023 - Disclosure - Note 16 - Stock-based Compensation link:calculationLink link:definitionLink link:presentationLink 024 - Disclosure - Note 17 - Income Taxes link:calculationLink link:definitionLink link:presentationLink 025 - Disclosure - Note 18 - Employee Benefit Plan link:calculationLink link:definitionLink link:presentationLink 026 - Disclosure - Note 19 - Commitments and Contingencies link:calculationLink link:definitionLink link:presentationLink 027 - Disclosure - Note 20 - Fair Value Measurements and Fair Value of Financial Instruments link:calculationLink link:definitionLink link:presentationLink 028 - Disclosure - Note 21 - Segments link:calculationLink link:definitionLink link:presentationLink 029 - Disclosure - Note 22 - Subsequent Events link:calculationLink link:definitionLink link:presentationLink 030 - Disclosure - Significant Accounting Policies (Policies) link:calculationLink link:definitionLink link:presentationLink 031 - Disclosure - Note 2 - Summary of Significant Accounting Policies (Tables) link:calculationLink link:definitionLink link:presentationLink 032 - Disclosure - Note 3 - Miscellaneous Financial Information (Tables) link:calculationLink link:definitionLink link:presentationLink 033 - Disclosure - Note 4 - Restricted Cash and Restricted Cash Equivalents (Tables) link:calculationLink link:definitionLink link:presentationLink 034 - Disclosure - Note 5 - Marketable Securities (Tables) link:calculationLink link:definitionLink link:presentationLink 035 - Disclosure - Note 7 - Intangible Assets (Tables) link:calculationLink link:definitionLink link:presentationLink 036 - Disclosure - Note 8 - Revenues From Contracts With Customers and Other Revenue (Tables) link:calculationLink link:definitionLink link:presentationLink 037 - Disclosure - Note 9 - Leases, Right-of-use Assets and Related Liabilities (Tables) link:calculationLink link:definitionLink link:presentationLink 038 - Disclosure - Note 10 - Inventories (Tables) link:calculationLink link:definitionLink link:presentationLink 039 - Disclosure - Note 11 - Property, Plant and Equipment (Tables) link:calculationLink link:definitionLink link:presentationLink 040 - Disclosure - Note 12 - Embedded Derivatives (Tables) link:calculationLink link:definitionLink link:presentationLink 041 - Disclosure - Note 13 - Accounts Payable and Accrued Liabilities (Tables) link:calculationLink link:definitionLink link:presentationLink 042 - Disclosure - Note 14 - Debt (Tables) link:calculationLink link:definitionLink link:presentationLink 043 - Disclosure - Note 15 - Equity Incentive Plans (Tables) link:calculationLink link:definitionLink link:presentationLink 044 - Disclosure - Note 16 - Stock-based Compensation (Tables) link:calculationLink link:definitionLink link:presentationLink 045 - Disclosure - Note 17 - Income Taxes (Tables) link:calculationLink link:definitionLink link:presentationLink 046 - Disclosure - Note 20 - Fair Value Measurements and Fair Value of Financial Instruments (Tables) link:calculationLink link:definitionLink link:presentationLink 047 - Disclosure - Note 21 - Segments (Tables) link:calculationLink link:definitionLink link:presentationLink 048 - Disclosure - Note 1 - Nature of Business and Financial Condition (Details Textual) link:calculationLink link:definitionLink link:presentationLink 049 - Disclosure - Note 2 - Summary of Significant Accounting Policies (Details Textual) link:calculationLink link:definitionLink link:presentationLink 050 - Disclosure - Note 2 - Summary of Significant Accounting Policies - Securities Potentially Dilute Calculation of Diluted Earnings Per Share (Details) link:calculationLink link:definitionLink link:presentationLink 051 - Disclosure - Note 3 - Miscellaneous Financial Information (Details Textual) link:calculationLink link:definitionLink link:presentationLink 052 - Disclosure - Note 3 - Miscellaneous Financial Information - Schedule of Revenue by Major Customer (Details) link:calculationLink link:definitionLink link:presentationLink 053 - Disclosure - Note 3 - Miscellaneous Financial Information - Restructuring Expense (Details) link:calculationLink link:definitionLink link:presentationLink 054 - Disclosure - Note 4 - Restricted Cash and Restricted Cash Equivalents (Details Textual) link:calculationLink link:definitionLink link:presentationLink 055 - Disclosure - Note 4 - Restricted Cash and Restricted Cash Equivalents - Receivable Bond (Details) link:calculationLink link:definitionLink link:presentationLink 056 - Disclosure - Note 5 - Marketable Securities (Details Textual) link:calculationLink link:definitionLink link:presentationLink 057 - Disclosure - Note 5 - Marketable Securities - Realized Gain (Loss) From Sale of Available-for-sale Marketable Securities (Details) link:calculationLink link:definitionLink link:presentationLink 058 - Disclosure - Note 6 - Axens License (Details Textual) link:calculationLink link:definitionLink link:presentationLink 059 - Disclosure - Note 7 - Intangible Assets (Details Textual) link:calculationLink link:definitionLink link:presentationLink 060 - Disclosure - Note 7 - Intangible Assets - Identifiable Intangible Assets (Details) link:calculationLink link:definitionLink link:presentationLink 061 - Disclosure - Note 7 - Intangible Assets - Amortization Expense (Details) link:calculationLink link:definitionLink link:presentationLink 062 - Disclosure - Note 7 - Intangible Assets - Estimated Net Amortization of Identifiable Intangible Assets (Details) link:calculationLink link:definitionLink link:presentationLink 063 - Disclosure - Note 8 - Revenues From Contracts With Customers and Other Revenue (Details Textual) link:calculationLink link:definitionLink link:presentationLink 064 - Disclosure - Note 8 - Revenues From Contracts With Customers and Other Revenue - Disaggregated Revenues (Details) link:calculationLink link:definitionLink link:presentationLink 065 - Disclosure - Note 9 - Leases, Right-of-use Assets and Related Liabilities (Details Textual) link:calculationLink link:definitionLink link:presentationLink 066 - Disclosure - Note 9 - Leases, Right-of-use Assets and Related Liabilities - Right-of-use Assets Under Operating and Financing Leases and Operating and Financing Lease Liabilities (Details) link:calculationLink link:definitionLink link:presentationLink 067 - Disclosure - Note 9 - Leases, Right-to-use Assets and Related Liabilities - Lease Costs (Details) link:calculationLink link:definitionLink link:presentationLink 068 - Disclosure - Note 9 - Leases, Right-to-Use Assets and Related Liabilities - Future Minimum Payments Under Non-cancelable Operating Leases (Details) link:calculationLink link:definitionLink link:presentationLink 069 - Disclosure - Note 10 - Inventories (Details Textual) link:calculationLink link:definitionLink link:presentationLink 070 - Disclosure - Note 10 - Inventories - Components of Inventory Balances (Details) link:calculationLink link:definitionLink link:presentationLink 071 - Disclosure - Note 11 - Property, Plant and Equipment - Property, Plant and Equipment by Classification (Details) link:calculationLink link:definitionLink link:presentationLink 072 - Disclosure - Note 11 - Property, Plant and Equipment - Depreciation and Amortization Expense (Details) link:calculationLink link:definitionLink link:presentationLink 073 - Disclosure - Note 12 - Embedded Derivatives (Details Textual) link:calculationLink link:definitionLink link:presentationLink 074 - Disclosure - Note 12 - Embedded Derivatives - Schedule of Shares Issued Upon Exercise of Warrants (Details) link:calculationLink link:definitionLink link:presentationLink 075 - Disclosure - Note 12 - Embedded Derivatives - Exercise of Warrants (Details) link:calculationLink link:definitionLink link:presentationLink 076 - Disclosure - Note 13 - Accounts Payable and Accrued Liabilities - Components Accounts Payable and Accrued Liabilities in Consolidated Balance Sheets (Details) link:calculationLink link:definitionLink link:presentationLink 077 - Disclosure - Note 14 - Debt (Details Textual) link:calculationLink link:definitionLink link:presentationLink 078 - Disclosure - Note 14 - Debt - Notes Payable - Other (Details) link:calculationLink link:definitionLink link:presentationLink 079 - Disclosure - Note 14 - Debt - Future Payments for Notes Payable - Other (Details) link:calculationLink link:definitionLink link:presentationLink 080 - Disclosure - Note 14 - Debt - Information Pertaining to Convertible Notes (Details) link:calculationLink link:definitionLink link:presentationLink 081 - Disclosure - Note 15 - Equity Incentive Plans (Details Textual) link:calculationLink link:definitionLink link:presentationLink 082 - Disclosure - Note 15 - Equity Incentive Plans - Restricted Common Stock and Non-qualified Stock Option Activity (Details) link:calculationLink link:definitionLink link:presentationLink 083 - Disclosure - Note 16 - Stock-based Compensation (Details Textual) link:calculationLink link:definitionLink link:presentationLink 084 - Disclosure - Note 16 - Stock-based Compensation - Stock-based Compensation Expense (Details) link:calculationLink link:definitionLink link:presentationLink 085 - Disclosure - Note 16 - Stock-based Compensation - Stock Option Award Activity (Details) link:calculationLink link:definitionLink link:presentationLink 086 - Disclosure - Note 16 - Stock-based Compensation - Stock Option Valuation Assumptions (Details) link:calculationLink link:definitionLink link:presentationLink 087 - Disclosure - Note 16 - Stock-based Compensation - Non-vested Restricted Stock (Details) link:calculationLink link:definitionLink link:presentationLink 088 - Disclosure - Note 17 - Income Taxes (Details Textual) link:calculationLink link:definitionLink link:presentationLink 089 - Disclosure - Note 17 - Income Taxes - Net Deferred Tax Assets (Details) link:calculationLink link:definitionLink link:presentationLink 090 - Disclosure - Note 17 - Income Taxes - Reconciling Items from Income Tax Computed at the Statutory Federal Rate (Details) link:calculationLink link:definitionLink link:presentationLink 091 - Disclosure - Note 18 - Employee Benefit Plan (Details Textual) link:calculationLink link:definitionLink link:presentationLink 092 - Disclosure - Note 19 - Commitments and Contingencies (Details Textual) link:calculationLink link:definitionLink link:presentationLink 093 - Disclosure - Note 20 - Fair Value Measurements and Fair Value of Financial Instruments (Details Textual) link:calculationLink link:definitionLink link:presentationLink 094 - Disclosure - Note 20 - Fair Value Measurements and Fair Value of Financial Instruments - Schedule of Carrying Value and Fair Value by Fair Value Hierarchy of Financial Instruments (Details) link:calculationLink link:definitionLink link:presentationLink 095 - Disclosure - Note 20 - Fair Value Measurements and Fair Value of Financial Instruments - Investments, Marketable Securities (Details) link:calculationLink link:definitionLink link:presentationLink 096 - Disclosure - Note 20 - Fair Value Measurements and Fair Value of Financial Instruments - Carrying Values and Estimated Fair Values (Details) link:calculationLink link:definitionLink link:presentationLink 097 - Disclosure - Note 21 - Segments (Details Textual) link:calculationLink link:definitionLink link:presentationLink 098 - Disclosure - Note 21 - Segments - Information on Business Segments (Details) link:calculationLink link:definitionLink link:presentationLink 099 - Disclosure - Note 22 - Subsequent Events (Details Textual) link:calculationLink link:definitionLink link:presentationLink